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Nandrolone Details

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Nandrolone is one of the most popular anabolic steroids, widely used in both medical and performance-enhancing fields. First developed in 1960, it was introduced worldwide in 1962 under the brand name Durabolin (Nandrolone Phenylpropionate). The most recognized version is Deca Durabolin (Nandrolone Decanoate), which has remained the dominant variant.

Functions & Traits:

  • Nandrolone is a -nortestosterone (19-nor) anabolic androgenic steroid, meaning it has a modified testosterone structure.
  • It has a higher anabolic rating than testosterone but a lower androgenic rating (37 compared to testosterone’s 100).
  • Key benefits:

  • Increases protein synthesis for muscle building.
  • Decreasesglucocorticoid hormones (stress hormones that degrade muscle).
  • Enhances IGF-1 production (vital for muscle recovery).
  • Improves nitrogen retention, avoiding muscle degradation.
  • Increases red blood cell production, increasing endurance.
  • Increases collagen synthesis and bone mineral density, helping joint and tendon health.
  • Medical Applications:

  • Used to cure muscle-wasting illnesses, weakness, anemia, and synthesis
  • Aids burnvictims, breast cancer patients, and developmental problems such as dwarfism (stress hormones that degrade muscle).
  • In America, it is mainly used inHIV patients and anti-aging therapy.
  • Side Effects

    • Estrogenic:Aromatizes 20% as much as testosterone, potentially leading to water retention and gynecomastia. Managed using Aromatase Inhibitors (AIs) like Arimidex.
    • Androgenic:Low androgenic risk, but acne, hair loss, and body hair growth can occur in predisposed individuals. Not recommended for women due to the risk of virilization (deep voice, body hair growth, clitoral enlargement).
    • Cardiovascular:Reduces good cholesterol (HDL), increasing cardiovascular risks. Best managed through a heart-healthy diet and regular cardio.
    • Testosterone Suppression:Suppresses natural testosterone production by 100%, requiring exogenous testosterone supplementation. Post Cycle Therapy (PCT) is necessary to restore natural levels.
    • Liver Toxicity:Not toxic to the liver and does not cause liver damage.

    Dosage & Administration

    • Medical Dosage:100-200mg per week for anemia and muscle-wasting conditions.
    • Performance Dosage:300-600mg per week is common, with 400mg being optimal for most users. Short ester versions (NPP) require more frequent injections (every other day).

    Availability

    • Widely available globally, but in the U.S., it is mostly sourced illegally or through compounding pharmacies.
    • Deca Durabolin (Nandrolone Decanoate) is the most common version, while Nandrolone Phenylpropionate (NPP) is less available.

    conclusion

    • Sustanon 250 is a versatile and potent testosterone compound used for TRT and enhancing athletic performance, though it comes with some risks and side effects that need to be managed carefully.

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